A subsidiary of
Dr. Reddy's Laboratories Ltd.


Why use the controlled release Microsphere Drug Delivery system?

Drugs with a short half-time often need to be administered regularly. Especially in case of injectable drugs, this causes much inconvenience to patients. They may need to visit care centers frequently or administer injections themselves. The use of a controlled release technology solves this problem.

Benefits of controlled release:

  • Drug release rates can be tailored to the needs of a specific application
  • Controlled release system protects drugs, especially proteins, that are otherwise rapidly destroyed by the body
  • Controlled release system can increase patient compliance


We offer our proprietary technology PolyActive or develop PLA/PLGA controlled release microsphere products with you

  • PLA and PLGA  for the delivery of peptides and small molecules
  • PolyActive for the delivery of proteins

We offer our partners 15 years of  Microsphere formulation & process development experience

  • Formulation development experts are fully equipped to develop new microsphere formulations or optimize existing formulations. Our experts already successfully completed more than 50 microsphere projects designed for subcutaneous, intramuscular, intravitreal, and intra-articular injections. Moreover, our teams have experience with multiple drugs from small to large, from stable to very instable molecules and for different therapeutic areas such as oncology, ophthalmology and inflammation. 

  • Process development experts are fully equipped to design and develop small to large scale, robust processes taking into account the GMP requirements. Our processes are immediately ready to be transferred to commercial operations (plug and play approach).

  • Analytical development experts are fully equipped to design and develop the required analytical methods.


OctoPlus fully implemented the Quality by Design methodology

What makes OctoPlus unique is the full implementation of  the Quality by Design methodology (QbD) and Process Analytical Technology (PAT) that ensure the development of highest quality processes in the most efficient way. Advanced statistical tools are used such as:

  • Design of Experiments (DoE) that enables our team to develop cost-effective, scalable and robust processes. 
  • Robustness by Design (RbD) that enables our teams to be able to develop robust, cost-effective analytical methods. 

QbD is strongly advised by the regulatory agencies  EMA, FDA and ICH.

Contact us if you are interested in partnering up  with us!       

OctoPlus strives for win-win partnerships

Vision & Mission

Our vision is, either independently or in collaboration, joining forces with the academic world and industry, to make innovative injectables available to a global market. Good health can't wait.


Our mission is to accelerate access to affordable and innovative injectables

Contact us

Meet OctoPlus at

Controlled Release Society
26-Jul-15 - 29-Jul-15 


BIO International Convention
15-Jun-15 - 18-Jun-15
Philadelphia, PA

AAPS Annual Meeting
25-Oct-15 - 29-Oct-15
Orlando, FL
2-Nov-15 - 4-Nov-15

More events

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