Why use Liposomal Drug Delivery system?
Sometimes an active pharmaceutical ingredient needs more than a simple formulation to become a successful drug. There might be solubility issues or perhaps the drug needs to be targeted at a specific part of the body. Liposomes offer elegant solutions to a number of challenges:
- To improve solubility
- To improve stability
- To modify pharmacokinetics
- To improve safety to the patient
We offer our partners 20 years of Liposomal formulation & process development experience
Formulation development experts are fully equipped to develop new liposomal formulations from scratch or optimize existing formulations. Our experts already successfully completed more than 35 liposomal projects and have experience with more than 60 different compounds.
Process development experts are fully equipped to design and develop small to large scale, robust processes taking into account all GMP requirements. Our processes are immediately ready to be transferred to commercial operations (plug and play approach).
Analytical development experts are fully equipped to design and develop the required analytical methods.
OctoPlus implemented the Quality by Design methodology
What makes OctoPlus unique is the full implementation of the Quality by Design methodology (QbD) and Process Analytical Technology (PAT) that ensure the development of highest quality processes in the most efficient way. Advanced statistical tools are used such as:
- Design of Experiments (DoE) that enables our team to develop cost-effective, scalable and robust processes.
- Robustness by Design (RbD) that enables our teams to be able to develop robust, cost-effective analytical methods.
QbD is advised by the regulatory agencies EMA, FDA and ICH.
Do you want to learn more about our capabilities? Download our capability sheet! /content/finder-upload/files/Capabilities%20Liposomes.pdf
Contact us if you are interested in partnering up with us!